I am creating centered drawer guides for this project. The objective is to lessen racking potential with the (mostly) wide drawers, as well use the opportunity to try a new approach.
There are two types of one-inch wide guides: for two full-shelves (fixed horizontal shelf and case bottom) and for three web frames. The upper web frame will support two narrower upper drawers. Guides for fixed shelves will be 1/4 inch proud set in 1/8 dadoes. These guides will be glued into the front portion of the dado and allowed to float beyond that allowing for wood movement.
The web frame guides (4 of these) are fixed into the front frame member and allowed to float at the rear.